Motif ID: FOX{D1,D2}.p2

Z-value: 1.942


Transcription factors associated with FOX{D1,D2}.p2:

Gene SymbolEntrez IDGene Name
Foxd1 15229 forkhead box D1
Foxd2 17301 forkhead box D2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1chr13_+_99124196-0.153.8e-02Click!
Foxd2chr4_-_1145814920.092.1e-01Click!


Activity profile for motif FOX{D1,D2}.p2.

activity profile for motif FOX{D1,D2}.p2


Sorted Z-values histogram for motif FOX{D1,D2}.p2

Sorted Z-values for motif FOX{D1,D2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{D1,D2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_45559866 28.363 Col5a2
collagen, type V, alpha 2
chr1_-_45559904 28.181 Col5a2
collagen, type V, alpha 2
chr3_+_96361879 27.009 NM_001009935
NM_023719
Txnip

thioredoxin interacting protein

chr10_+_97028456 25.912 Lum
lumican
chr16_+_48872720 25.045 NM_181596
Retnlg
resistin like gamma
chr16_+_48872756 23.684 Retnlg
resistin like gamma
chr1_+_51346108 22.264 Sdpr
serum deprivation response
chr1_+_51346086 20.410 Sdpr
serum deprivation response
chr1_-_195068455 20.401 NM_001044751
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
chr1_+_51345952 20.280 NM_138741
Sdpr
serum deprivation response
chr7_-_118089700 19.388 NM_010826
Mrvi1
MRV integration site 1
chr10_+_96079634 19.220 NM_007569
Btg1
B-cell translocation gene 1, anti-proliferative
chr1_-_45559700 18.520 Col5a2
collagen, type V, alpha 2
chr1_-_45560001 18.474 NM_007737
Col5a2
collagen, type V, alpha 2
chr10_+_115254308 18.148 NM_001168679
NM_001168680
NM_146010
Tspan8


tetraspanin 8


chr6_-_5446277 18.055 NM_013743
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr17_+_47641999 17.569 NM_001081635
NM_001081636
Ccnd3

cyclin D3

chr10_-_117252126 17.374


chr8_-_25549415 17.054 NM_026931
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr8_-_25549374 16.429 1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr10_-_116786025 15.927 Cpsf6
cleavage and polyadenylation specific factor 6
chr19_+_9092973 15.578 Ahnak
AHNAK nucleoprotein (desmoyokin)
chr6_-_83486194 15.412 NM_009610
Actg2
actin, gamma 2, smooth muscle, enteric
chr10_-_60915251 15.323 NM_010124
Eif4ebp2
eukaryotic translation initiation factor 4E binding protein 2
chr1_+_45390415 15.122 Col3a1
collagen, type III, alpha 1
chr9_+_7792286 14.987 Tmem123
transmembrane protein 123
chr6_+_135313010 14.934 Emp1
epithelial membrane protein 1
chr17_-_71201055 14.869 NM_001164075
Tgif1
TGFB-induced factor homeobox 1
chr4_+_144483110 14.826 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_94405963 14.765 NM_013690
Tek
endothelial-specific receptor tyrosine kinase
chr2_-_28771940 14.682 NM_019446
NM_001164186
Barhl1

BarH-like 1 (Drosophila)

chr6_+_135312948 14.513 NM_010128
Emp1
epithelial membrane protein 1
chr6_+_108804370 14.381 Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr4_+_144482979 14.270 NM_011303
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_94406190 14.190 Tek
endothelial-specific receptor tyrosine kinase
chr2_+_74536666 14.155 Hoxd9
homeobox D9
chr5_-_17394564 14.111 Cd36
CD36 antigen
chr3_+_52072302 14.006 Foxo1
forkhead box O1
chr1_+_45402907 13.823 Col3a1
collagen, type III, alpha 1
chr4_+_144482722 13.678 NM_001172424
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr3_-_89084872 13.466 NM_001162425
Efna1
ephrin A1
chr15_-_66392539 13.285 NM_172514
Tmem71
transmembrane protein 71
chr6_+_68375560 13.096 Igkv16-104
immunoglobulin kappa variable 16-104
chr3_+_52072251 13.045 NM_019739
Foxo1
forkhead box O1
chr4_+_133871031 12.827 NM_001039048
Trim63
tripartite motif-containing 63
chr5_+_20878459 12.818 NM_008013
Fgl2
fibrinogen-like protein 2
chr9_-_45763300 12.671 NM_172257
Sidt2
SID1 transmembrane family, member 2
chr6_+_34813131 12.458 NM_197986
Tmem140
transmembrane protein 140
chr16_+_24448176 12.398 NM_001145952
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_51828671 12.299 NM_001141948
NM_001141949
NM_019401
Nmi


N-myc (and STAT) interactor


chr19_-_38199737 11.771 NM_001159487
Rbp4
retinol binding protein 4, plasma
chr19_+_46697882 11.431 NM_001177813
D19Wsu162e
DNA segment, Chr 19, Wayne State University 162, expressed
chr5_-_91069499 11.425 NM_028478
Rassf6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_59562054 11.336 NM_144904
NM_178164
Rod1

ROD1 regulator of differentiation 1 (S. pombe)

chr11_+_94811409 11.111 Col1a1
collagen, type I, alpha 1
chr3_-_29912113 10.922 NM_007963
Mecom
MDS1 and EVI1 complex locus
chr17_+_34400152 10.889 NM_207105
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr3_-_29911982 10.800 Mecom
MDS1 and EVI1 complex locus
chr3_-_101091814 10.797 NM_013486
Cd2
CD2 antigen
chr17_+_29629987 10.791 Pim1
proviral integration site 1
chr2_-_52194317 10.759 NM_010889
Neb
nebulin
chr5_+_31554072 10.699 NM_027221
Krtcap3
keratinocyte associated protein 3
chr11_-_106576550 10.685 Pecam1
platelet/endothelial cell adhesion molecule 1
chr6_+_34548512 10.548 Cald1
caldesmon 1
chr17_+_35331446 10.178 NM_008518
Ltb
lymphotoxin B
chr7_-_91838299 10.136 Zfand6
zinc finger, AN1-type domain 6
chr11_-_106576464 9.978 Pecam1
platelet/endothelial cell adhesion molecule 1
chr9_+_50302624 9.965 NM_029639
1600029D21Rik
RIKEN cDNA 1600029D21 gene
chr7_-_26175113 9.905 NM_001039507
Lipe
lipase, hormone sensitive
chr7_+_82600419 9.805 NM_029332
Akap13
A kinase (PRKA) anchor protein 13
chr2_-_51828440 9.732 Nmi
N-myc (and STAT) interactor
chr15_-_58046428 9.645 NM_026346
Fbxo32
F-box protein 32
chr1_-_196957466 9.635 Cr1l
complement component (3b/4b) receptor 1-like
chr1_-_54983048 9.540 Ankrd44
ankyrin repeat domain 44
chr15_-_97662101 9.446 NM_019572
Hdac7
histone deacetylase 7
chr6_+_70676428 9.381


chr11_-_106576585 9.078 NM_001032378
NM_008816
Pecam1

platelet/endothelial cell adhesion molecule 1

chr10_-_92773579 9.048 Elk3
ELK3, member of ETS oncogene family
chr7_-_87547589 9.011 NM_011046
Furin
furin (paired basic amino acid cleaving enzyme)
chr12_-_32635399 8.960 NM_153198
NM_177993
Hbp1

high mobility group box transcription factor 1

chr5_-_17394776 8.909 NM_001159558
Cd36
CD36 antigen
chr2_+_127951773 8.888 NM_009754
NM_207680
NM_207681
Bcl2l11


BCL2-like 11 (apoptosis facilitator)


chr11_+_87895626 8.871 Vezf1
vascular endothelial zinc finger 1
chr4_+_132686434 8.770 NM_153423
Wasf2
WAS protein family, member 2
chr12_-_56087322 8.751 NM_013815
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr14_+_34899165 8.716 NM_013473
Anxa8
annexin A8
chr10_-_92773778 8.686 NM_013508
Elk3
ELK3, member of ETS oncogene family
chr11_-_120587426 8.626


chr11_+_98245124 8.607 NM_011540
Tcap
titin-cap
chr7_-_97103461 8.588


chr6_-_52184909 8.563 NM_008263
Hoxa10
homeobox A10
chr12_-_32635061 8.537 Hbp1
high mobility group box transcription factor 1
chr2_+_35163157 8.530 Gsn
gelsolin
chr11_+_82724754 8.529 NM_178680
Unc45b
unc-45 homolog B (C. elegans)
chr1_+_173155414 8.465 Apoa2
apolipoprotein A-II
chr15_+_79178063 8.456 NM_010755
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr19_-_38117813 8.445 Myof
myoferlin
chr6_+_122463595 8.429 Mfap5
microfibrillar associated protein 5
chr6_+_113102884 8.389 Setd5
SET domain containing 5
chr9_-_45762994 8.384 Sidt2
SID1 transmembrane family, member 2
chr10_-_67599315 8.267 Arid5b
AT rich interactive domain 5B (MRF1-like)
chr2_-_163470870 8.235 NM_012032
Serinc3
serine incorporator 3
chr12_+_113917038 8.118 NM_001100460
Zbtb42
zinc finger and BTB domain containing 42
chr11_-_106576380 8.085 Pecam1
platelet/endothelial cell adhesion molecule 1
chr11_+_28821585 8.083 Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr1_+_89999782 8.024 NM_201410
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr10_-_24647173 8.010 Arg1
arginase, liver
chr15_+_61816895 7.989 NM_001177352
NM_001177353
NM_001177354
NM_010849
Myc



myelocytomatosis oncogene



chr15_+_3220766 7.965 NM_001042613
NM_001042614
NM_009155
Sepp1


selenoprotein P, plasma, 1


chr9_-_45763233 7.939 Sidt2
SID1 transmembrane family, member 2
chr8_+_47619706 7.829


chr2_+_133378934 7.795 NM_007553
Bmp2
bone morphogenetic protein 2
chr3_-_145312928 7.791 NM_010516
Cyr61
cysteine rich protein 61
chr15_+_79177959 7.777 Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr4_-_49562319 7.754 NM_144903
Aldob
aldolase B, fructose-bisphosphate
chr11_+_74433123 7.640 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr7_+_97357406 7.622 Picalm
phosphatidylinositol binding clathrin assembly protein
chr11_+_96790581 7.604 NM_146026
Prr15l
proline rich 15-like
chr1_+_132762353 7.589 NM_026976
Faim3
Fas apoptotic inhibitory molecule 3
chr3_+_19857053 7.459 NM_001042611
NM_007752
Cp

ceruloplasmin

chr18_+_60535680 7.442 NM_001146275
NM_021792
Iigp1

interferon inducible GTPase 1

chrX_+_160578411 7.429 NM_027286
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr12_-_87419813 7.398 NM_009368
Tgfb3
transforming growth factor, beta 3
chr5_+_139865857 7.392 NM_001038703
Gpr146
G protein-coupled receptor 146
chr1_+_173155184 7.374 NM_013474
Apoa2
apolipoprotein A-II
chr2_+_121854287 7.310 NM_144545
Eif3j
eukaryotic translation initiation factor 3, subunit J
chr4_-_49562400 7.286 Aldob
aldolase B, fructose-bisphosphate
chr7_-_52359079 7.278 NM_010189
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr1_+_132762248 7.197 Faim3
Fas apoptotic inhibitory molecule 3
chr12_+_35731853 7.157 NM_001014973
Snx13
sorting nexin 13
chr19_-_34329804 7.140 NM_007392
Acta2
actin, alpha 2, smooth muscle, aorta
chrX_-_137077639 7.137 NM_010286
Tsc22d3
TSC22 domain family, member 3
chr6_-_72383243 7.121 Mat2a
methionine adenosyltransferase II, alpha
chr15_+_61817102 7.059 Myc
myelocytomatosis oncogene
chr7_+_86058650 7.023 NM_020583
Isg20
interferon-stimulated protein
chr14_+_31692725 6.965 Mustn1
musculoskeletal, embryonic nuclear protein 1
chr1_+_180179405 6.877 Pppde1
PPPDE peptidase domain containing 1
chr4_+_64785207 6.834 NM_021362
Pappa
pregnancy-associated plasma protein A
chr15_+_3220999 6.833 Sepp1
selenoprotein P, plasma, 1
chr5_+_116005777 6.815 Pxn
paxillin
chr1_+_90097175 6.806 NM_013701
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
chr1_+_52176281 6.804 NM_009283
Stat1
signal transducer and activator of transcription 1
chr13_-_94269673 6.782 Jmy
junction-mediating and regulatory protein
chr17_-_34134101 6.757 H2-K1
histocompatibility 2, K1, K region
chr15_+_3220994 6.745 Sepp1
selenoprotein P, plasma, 1
chr19_+_5877812 6.732 Slc25a45
solute carrier family 25, member 45
chr6_+_70648433 6.723 Igkv3-2
immunoglobulin kappa variable 3-2
chr12_-_102988893 6.719 Fbln5
fibulin 5
chr1_+_45401659 6.717 Col3a1
collagen, type III, alpha 1
chr2_-_84614976 6.710 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr10_+_96945057 6.679 Dcn
decorin
chr7_-_26573483 6.608 NM_001190974
NM_001190975
NM_009465
Axl


AXL receptor tyrosine kinase


chr15_-_97661807 6.593 Hdac7
histone deacetylase 7
chr15_+_80541675 6.504 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr2_-_59963586 6.491 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_-_84662710 6.491 NM_024230
Smtnl1
smoothelin-like 1
chr7_+_148153974 6.472 NM_001112715
Ifitm1
interferon induced transmembrane protein 1
chr2_+_69508174 6.414 NM_001081087
Kbtbd10
kelch repeat and BTB (POZ) domain containing 10
chr6_-_48658182 6.373 Gimap6
GTPase, IMAP family member 6
chr1_-_164816645 6.366 Fmo2
flavin containing monooxygenase 2
chr14_+_75536138 6.365 NM_008879
Lcp1
lymphocyte cytosolic protein 1
chr6_-_87793459 6.311 Cnbp
cellular nucleic acid binding protein
chr19_-_38118066 6.304 NM_001099634
Myof
myoferlin
chr2_-_163470826 6.265 Serinc3
serine incorporator 3
chr19_+_5878465 6.261 NM_134154
Slc25a45
solute carrier family 25, member 45
chr8_-_124948837 6.258


chr5_-_148118681 6.244 NM_007673
Cdx2
caudal type homeobox 2
chr17_-_34134309 6.223 H2-K1
histocompatibility 2, K1, K region
chr2_+_162758440 6.199 Srsf6
serine/arginine-rich splicing factor 6
chr11_-_86621130 6.148 NM_026191
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr7_-_110962324 6.111 Hbb-b1
Hbb-b2
hemoglobin, beta adult major chain
hemoglobin, beta adult minor chain
chr9_+_69137659 6.086 Rora
RAR-related orphan receptor alpha
chr18_+_61747381 6.069 Csnk1a1
casein kinase 1, alpha 1
chr1_+_59543450 6.043


chr1_-_152840432 6.033 NM_001024720
Hmcn1
hemicentin 1
chr12_-_85791928 6.018 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr11_-_100259048 6.001 NM_010593
Jup
junction plakoglobin
chr3_+_96636596 5.993 NM_001146001
Pdzk1
PDZ domain containing 1
chr1_-_71686889 5.957 Fn1
fibronectin 1
chr13_+_49704471 5.951 Ogn
osteoglycin
chr14_+_56179818 5.916 Dcaf11
DDB1 and CUL4 associated factor 11
chr2_-_163470787 5.901 Serinc3
serine incorporator 3
chr7_+_120351012 5.874 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr5_-_66000506 5.870 B230308N11Rik
RIKEN cDNA B230308N11 gene
chr13_+_49639847 5.791 Aspn
asporin
chr13_-_99585065 5.787 Fcho2
FCH domain only 2
chr5_-_87998014 5.771 NM_016771
Sult1d1
sulfotransferase family 1D, member 1
chr3_-_130951398 5.756 Hadh
hydroxyacyl-Coenzyme A dehydrogenase
chr19_+_34365195 5.737 Fas
Fas (TNF receptor superfamily member 6)
chr15_+_79178408 5.708 Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr1_+_136311948 5.679 NM_028320
Adipor1
adiponectin receptor 1
chr5_-_87997908 5.678 Sult1d1
sulfotransferase family 1D, member 1
chr16_+_33829715 5.642 NM_001145884
NM_010580
Itgb5

integrin beta 5

chr7_+_130337876 5.641 Tnrc6a
trinucleotide repeat containing 6a
chr15_-_96861590 5.635 Slc38a4
solute carrier family 38, member 4
chr14_+_56179739 5.629 NM_001199009
Dcaf11
DDB1 and CUL4 associated factor 11
chr5_-_123439064 5.627 NM_001003953
Kdm2b
lysine (K)-specific demethylase 2B
chr2_+_151398367 5.627 NM_145535
Sdcbp2
syndecan binding protein (syntenin) 2
chr14_-_55725370 5.548 NM_007455
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr18_+_5046584 5.524 NM_153153
Svil
supervillin

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.13 8.37e-12 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.45 1.35e-10 GO:0019222 regulation of metabolic process
1.63 2.58e-10 GO:0048519 negative regulation of biological process
1.50 2.62e-10 GO:0060255 regulation of macromolecule metabolic process
1.28 3.90e-10 GO:0008152 metabolic process
2.07 1.75e-09 GO:0010557 positive regulation of macromolecule biosynthetic process
1.30 3.11e-09 GO:0044238 primary metabolic process
1.53 5.22e-09 GO:0048518 positive regulation of biological process
1.46 5.27e-09 GO:0031323 regulation of cellular metabolic process
1.56 5.30e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.46 6.20e-09 GO:0080090 regulation of primary metabolic process
1.30 6.77e-09 GO:0044237 cellular metabolic process
1.61 1.21e-08 GO:0048523 negative regulation of cellular process
1.56 1.45e-08 GO:0048522 positive regulation of cellular process
1.82 1.60e-08 GO:0010604 positive regulation of macromolecule metabolic process
1.96 2.04e-08 GO:0009891 positive regulation of biosynthetic process
1.57 2.20e-08 GO:0051252 regulation of RNA metabolic process
1.57 3.40e-08 GO:0006355 regulation of transcription, DNA-dependent
1.51 3.98e-08 GO:0009889 regulation of biosynthetic process
2.14 6.10e-08 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.95 6.62e-08 GO:0031328 positive regulation of cellular biosynthetic process
1.75 8.10e-08 GO:0009893 positive regulation of metabolic process
2.07 9.91e-08 GO:0045893 positive regulation of transcription, DNA-dependent
1.53 1.22e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.51 1.26e-07 GO:0010468 regulation of gene expression
1.76 1.28e-07 GO:0009653 anatomical structure morphogenesis
2.08 2.05e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
2.04 2.22e-07 GO:0051254 positive regulation of RNA metabolic process
1.76 2.38e-07 GO:0031325 positive regulation of cellular metabolic process
1.49 2.70e-07 GO:0031326 regulation of cellular biosynthetic process
1.32 3.31e-07 GO:0043170 macromolecule metabolic process
1.98 3.75e-07 GO:0010628 positive regulation of gene expression
1.89 4.02e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.48 6.77e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.13 9.01e-07 GO:0051253 negative regulation of RNA metabolic process
2.06 1.07e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.13 1.07e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.47 1.08e-06 GO:0051171 regulation of nitrogen compound metabolic process
2.01 1.10e-06 GO:0031327 negative regulation of cellular biosynthetic process
2.05 1.86e-06 GO:0010629 negative regulation of gene expression
1.43 1.90e-06 GO:0009058 biosynthetic process
1.89 2.11e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
2.15 2.15e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.03 2.23e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.90 2.56e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.22 2.61e-06 GO:0072358 cardiovascular system development
2.22 2.61e-06 GO:0072359 circulatory system development
1.84 2.90e-06 GO:0031324 negative regulation of cellular metabolic process
2.35 3.19e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.96 3.55e-06 GO:0009890 negative regulation of biosynthetic process
1.79 4.34e-06 GO:0009892 negative regulation of metabolic process
2.69 4.73e-06 GO:0001501 skeletal system development
1.32 5.54e-06 GO:0044260 cellular macromolecule metabolic process
1.41 1.86e-05 GO:0044249 cellular biosynthetic process
1.36 3.32e-05 GO:0006807 nitrogen compound metabolic process
2.33 5.64e-05 GO:0009725 response to hormone stimulus
1.55 5.90e-05 GO:0048513 organ development
1.45 6.03e-05 GO:0009059 macromolecule biosynthetic process
1.79 8.16e-05 GO:0042127 regulation of cell proliferation
1.42 1.33e-04 GO:0010467 gene expression
3.01 1.37e-04 GO:0043434 response to peptide hormone stimulus
1.53 1.55e-04 GO:0006351 transcription, DNA-dependent
1.93 1.69e-04 GO:0070887 cellular response to chemical stimulus
1.53 1.74e-04 GO:0032774 RNA biosynthetic process
2.35 2.07e-04 GO:0001944 vasculature development
1.52 2.71e-04 GO:0042221 response to chemical stimulus
1.80 2.85e-04 GO:0009790 embryo development
1.36 2.96e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 3.41e-04 GO:0048731 system development
1.33 3.75e-04 GO:0034641 cellular nitrogen compound metabolic process
1.68 4.10e-04 GO:0010033 response to organic substance
1.35 4.13e-04 GO:0032502 developmental process
1.40 4.16e-04 GO:0048856 anatomical structure development
1.42 5.19e-04 GO:0034645 cellular macromolecule biosynthetic process
1.72 6.51e-04 GO:0002376 immune system process
1.90 7.18e-04 GO:0009887 organ morphogenesis
2.34 9.53e-04 GO:0001568 blood vessel development
1.36 9.58e-04 GO:0007275 multicellular organismal development
2.11 1.00e-03 GO:0009719 response to endogenous stimulus
1.67 1.03e-03 GO:0010941 regulation of cell death
1.68 1.07e-03 GO:0043067 regulation of programmed cell death
2.04 1.12e-03 GO:0043069 negative regulation of programmed cell death
1.68 1.17e-03 GO:0042981 regulation of apoptosis
1.54 1.45e-03 GO:0051239 regulation of multicellular organismal process
2.03 1.66e-03 GO:0043066 negative regulation of apoptosis
2.49 2.06e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.47 2.49e-03 GO:0065008 regulation of biological quality
2.07 2.81e-03 GO:0032583 regulation of gene-specific transcription
1.40 2.98e-03 GO:0016070 RNA metabolic process
2.14 3.04e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.21 3.07e-03 GO:0040012 regulation of locomotion
1.95 4.16e-03 GO:0060548 negative regulation of cell death
1.36 5.09e-03 GO:0090304 nucleic acid metabolic process
2.19 5.50e-03 GO:0051270 regulation of cellular component movement
2.23 8.27e-03 GO:0030334 regulation of cell migration
1.66 9.19e-03 GO:2000026 regulation of multicellular organismal development
2.06 9.57e-03 GO:0007389 pattern specification process
2.20 1.16e-02 GO:2000145 regulation of cell motility
13.81 1.21e-02 GO:0010761 fibroblast migration
1.46 1.23e-02 GO:0048583 regulation of response to stimulus
2.71 1.31e-02 GO:0042060 wound healing
3.35 1.33e-02 GO:0031589 cell-substrate adhesion
2.64 1.35e-02 GO:0006916 anti-apoptosis
2.43 1.59e-02 GO:0034097 response to cytokine stimulus
1.90 1.68e-02 GO:0071310 cellular response to organic substance
2.06 1.89e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.32 1.89e-02 GO:0016043 cellular component organization
6.98 1.90e-02 GO:0045661 regulation of myoblast differentiation
2.04 2.53e-02 GO:0002520 immune system development
4.80 2.60e-02 GO:0048641 regulation of skeletal muscle tissue development
2.05 2.61e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.85 2.73e-02 GO:0009792 embryo development ending in birth or egg hatching
4.07 3.06e-02 GO:0010906 regulation of glucose metabolic process
1.57 3.10e-02 GO:0050793 regulation of developmental process
5.74 3.35e-02 GO:0010717 regulation of epithelial to mesenchymal transition
4.68 3.43e-02 GO:0050818 regulation of coagulation
4.68 3.43e-02 GO:0051153 regulation of striated muscle cell differentiation
16.58 3.52e-02 GO:0030540 female genitalia development
1.84 3.69e-02 GO:0043009 chordate embryonic development
1.81 4.04e-02 GO:0008284 positive regulation of cell proliferation
1.30 4.15e-02 GO:0071840 cellular component organization or biogenesis
3.68 4.81e-02 GO:0007160 cell-matrix adhesion

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.18 1.15e-09 GO:0005622 intracellular
1.19 1.33e-09 GO:0044424 intracellular part
1.21 1.09e-08 GO:0043226 organelle
1.90 3.80e-08 GO:0044421 extracellular region part
1.20 6.15e-08 GO:0043229 intracellular organelle
1.59 2.78e-07 GO:0005576 extracellular region
2.00 3.58e-07 GO:0005615 extracellular space
1.21 5.51e-07 GO:0043227 membrane-bounded organelle
1.21 7.91e-07 GO:0043231 intracellular membrane-bounded organelle
1.29 7.06e-06 GO:0005634 nucleus
1.18 1.65e-04 GO:0005737 cytoplasm
2.22 3.89e-04 GO:0042598 vesicular fraction
2.22 4.98e-04 GO:0005792 microsome
2.40 1.37e-03 GO:0016323 basolateral plasma membrane
1.73 2.53e-03 GO:0044451 nucleoplasm part
1.21 2.89e-03 GO:0044444 cytoplasmic part
1.24 4.99e-03 GO:0044422 organelle part
2.83 7.95e-03 GO:0044420 extracellular matrix part
1.07 1.11e-02 GO:0005623 cell
1.07 1.11e-02 GO:0044464 cell part
1.49 1.31e-02 GO:0000267 cell fraction
7.65 2.08e-02 GO:0005583 fibrillar collagen
5.10 3.70e-02 GO:0005581 collagen
1.22 4.04e-02 GO:0044446 intracellular organelle part
2.29 4.69e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.37 1.47e-12 GO:0005515 protein binding
1.21 1.70e-12 GO:0005488 binding
1.88 1.20e-05 GO:0001071 nucleic acid binding transcription factor activity
1.88 1.20e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
3.63 3.31e-05 GO:0019838 growth factor binding
1.89 9.41e-05 GO:0043565 sequence-specific DNA binding
1.72 1.65e-04 GO:0030528 transcription regulator activity
1.67 1.98e-04 GO:0005102 receptor binding
1.48 3.43e-04 GO:0003677 DNA binding
1.38 4.69e-04 GO:0003676 nucleic acid binding
2.00 2.12e-03 GO:0008289 lipid binding
1.65 3.04e-03 GO:0019899 enzyme binding
3.87 6.06e-03 GO:0005496 steroid binding
2.09 6.30e-03 GO:0008134 transcription factor binding
6.03 1.56e-02 GO:0005520 insulin-like growth factor binding
2.79 1.71e-02 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
1.96 4.36e-02 GO:0016564 transcription repressor activity